Dosing and
Administration

Once-daily, easy-to-follow regimen so that patients with partial seizures can start and stay with Oxtellar XR (oxcarbazepine).

For adult patients with partial seizures1

Tablets shown are not actual size

  • 1 week to 1200 mg/day once-daily maintenance dose in adults1
  • Initiate treatment at a dosage of 600 mg/day given orally once daily for 1 week. Subsequent dosage increases can be made at weekly intervals in 600 mg/day increments1
  • Maintain at 1200 mg/day to 2400 mg/day once daily1

For pediatric patients (aged 6 to <17 years) with partial seizures1

  • Initiate with 8 mg/kg to 10 mg/kg once per day.
  • Titrate to target dose over 2 to 3 weeks.
  • Increase in weekly increments of 8 mg/kg to 10 mg/kg once daily, not to exceed 600 mg, to achieve target daily dose

For geriatric patients with partial seizures1

  • Start at a lower dosage (300 mg/day or 450 mg/day)
  • Subsequent dosage increases can be made at weekly intervals in increments of 300 mg/day to 450 mg/day to achieve the desired clinical effect

Administering Oxtellar XR (oxcarbazepine)1

  • Oxtellar XR (oxcarbazepine) should be taken as a single daily dose on an empty stomach
    • Patients should take Oxtellar XR (oxcarbazepine) at least 1 hour before or at least 2 hours after meals
    • When Oxtellar XR (oxcarbazepine) is taken with food, adverse reactions are more likely to occur because of increased peak plasma concentration levels
  • Oxtellar XR (oxcarbazepine) tablets should be swallowed whole. Do not cut, crush, or chew the tablets
    • Lower-strength tablets (150 mg tablets) are available for pediatric patients or patients with difficulty swallowing
  • For patients previously treated with Trileptal® (oxcarbazepine), higher doses of Oxtellar XR (oxcarbazepine) may be necessary
  • Enzyme inducing antiepileptic drugs such as carbamazepine, phenobarbital, and phenytoin decrease the exposure to MHD, the active metabolite of Oxtellar XR. Dosage increases or discontinuation of enzyme inducers may be necessary.
  • In patients with several renal impairment, initiate Oxtellar XR at a lower starting dose and increase, if necessary, at a slower than usual rate until the desired clinical response is achieved.

  • Use of Oxtellar XR with certain hormonal contraceptives may decrease hormone plasma levels and render these contraceptives less effective. Additional or alternative non-hormonal forms of contraception are recommended.

Empty stomach icon

Take Oxtellar XR (oxcarbazepine) on an empty stomach, at least 1 hour before or at least 2 hours after a meal.

QD Dosing with 3 dosage strength1

Oxtellar XR (oxcarbazepine) QD dosing with three dosage strengths

Tablets shown are not actual size

chart

Oxtellar XR helped
significantly reduce partial-onset
seizure frequency

Script

Get your patient started
on Oxtellar XR